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RNF139 抗体 (N-Term)

RNF139 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774685
发货至: 中国
  • 抗原 See all RNF139 抗体
    RNF139 (Ring Finger Protein 139 (RNF139))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 17
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马
    宿主
    • 28
    • 3
    • 1
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF139 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    Western Blotting (WB)
    序列
    SQRSLFKFYT YSSAFLLAAT SVLVNYYASL HIDFYGAYNT SAFGIELLPR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against RNF139. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human RNF139
    Top Product
    Discover our top product RNF139 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 664 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RNF139 (Ring Finger Protein 139 (RNF139))
    别名
    RNF139 (RNF139 产品)
    别名
    HRCA1 antibody, RCA1 antibody, TRC8 antibody, 4930555P18Rik antibody, zgc:175173 antibody, rnf139 antibody, ring finger protein 139 antibody, ring finger protein 139 S homeolog antibody, RNF139 antibody, Rnf139 antibody, rnf139 antibody, rnf139.S antibody
    背景
    RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
    Alias Symbols: HRCA1, MGC31961, RCA1, TRC8
    Protein Interaction Partner: HM13, HLA-C, UBE2G2, AUP1, UBC, INSIG1, HMGCR, INSIG2, TMUB1, ERLIN2, ERLIN1, SCAP, SEC24B, SREBF2, EIF3A, UBE2U, UBE2Z, UBE2H, COPS5, VHL,
    Protein Size: 664
    分子量
    76 kDa
    基因ID
    11236
    NCBI登录号
    NM_007218, NP_009149
    UniProt
    Q8WU17
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