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RNF139 抗体 (AA 604-636)

RNF139 适用: 人 WB 宿主: 兔 Polyclonal RB54248 unconjugated
产品编号 ABIN6242550
发货至: 中国
  • 抗原 See all RNF139 抗体
    RNF139 (Ring Finger Protein 139 (RNF139))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 604-636
    适用
    • 18
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 3
    • 1
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF139 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RNF139 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 604-636 amino acids from human RNF139.
    克隆位点
    RB54248
    亚型
    Ig Fraction
    Top Product
    Discover our top product RNF139 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    RNF139 (Ring Finger Protein 139 (RNF139))
    别名
    RNF139 (RNF139 产品)
    别名
    HRCA1 antibody, RCA1 antibody, TRC8 antibody, 4930555P18Rik antibody, zgc:175173 antibody, rnf139 antibody, ring finger protein 139 antibody, ring finger protein 139 S homeolog antibody, RNF139 antibody, Rnf139 antibody, rnf139 antibody, rnf139.S antibody
    背景
    E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
    分子量
    75994
    UniProt
    Q8WU17
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