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RGS18 产品

(Regulator of G-Protein Signalling 18 (RGS18))

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This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

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Featured RGS18 Categories

RGS18 抗体

High quality antibodies with extensive validation data.

RGS18 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RGS18 抗体

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Reactivity Human
Application ELISA, WB, IHC
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Cat. No. ABIN185237
Quantity 100 μg
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Reactivity Human
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Cat. No. ABIN7167593
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Cat. No. ABIN528640
Quantity 200 μL
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Recommended RGS18 蛋白

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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3087199
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Reactivity Mouse
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Cat. No. ABIN3128152
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Latest Publications for our RGS18 Products

Iwai, Koike, Ohshima, Miyatake, Uchiyama, Saeki, Ishii: "RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 22, Issue 10, pp. 1612-20, (2007) (PubMed).

Park, Klug, Li, Jerabek, Li, Nanamori, Neubig, Hood, Weissman, Clarke: "Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells." in: The Journal of biological chemistry, Vol. 276, Issue 2, pp. 915-23, (2001) (PubMed).

Synonyms and alternative names related to RGS18

regulator of G-protein signaling 18 (RGS18), regulator of G protein signaling 18 (RGS18), regulator of G-protein signaling 18 (rgs18), regulator of G-protein signaling 18 (LOC100224724), regulator of G-protein signaling 18 (Rgs18), RGS13, RGS18, rgs18

Protein level used designations for RGS18

  • regulator of G-protein signalling 18
  • regulator of G-protein signaling 18
  • regulator of G-protein signalling 13
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