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RGS13 产品

(Regulator of G-Protein Signaling 13 (RGS13))

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The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008].

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Featured RGS13 Categories

RGS13 抗体

High quality antibodies with extensive validation data.

RGS13 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RGS13 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
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  • (3)
Cat. No. ABIN1327513
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN519779
Quantity 100 μg
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Reactivity Human
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN1881748
Quantity 400 μL
Datasheet Datasheet

Recommended RGS13 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
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Cat. No. ABIN1317935
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317934
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3087217
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RGS13 Products

Wang, Lippman, Lee, Yang, Khuri, Kim, Lin, Chang, Lotan, Hong, Wu: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." in: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).

Bansal, DiVietro, Kuehn, Rao, Nocka, Gilfillan, Druey: "RGS13 controls g protein-coupled receptor-evoked responses of human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 7882-90, (2008) (PubMed).

Bansal, Xie, Rao, Nocka, Druey: "Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13." in: Nature immunology, Vol. 9, Issue 1, pp. 73-80, (2007) (PubMed).

Han, Huang, Kim, Kehrl: "RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization." in: Journal of leukocyte biology, Vol. 79, Issue 6, pp. 1357-68, (2006) (PubMed).

Islam, Asplund, Lindvall, Nygren, Liden, Kimby, Christensson, Smith, Sander: "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma." in: Leukemia, Vol. 17, Issue 9, pp. 1880-90, (2003) (PubMed).

Synonyms and alternative names related to RGS13

regulator of G protein signaling 13 (RGS13), regulator of G-protein signaling 13 (Rgs13), RGD1562103

Protein level used designations for RGS13

  • regulator of G-protein signalling 13
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