RFX1 产品
(Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))
Categories
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. [provided by RefSeq, Jul 2008].
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Featured RFX1 Categories
Recommended RFX1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7159682
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1537643
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Mouse, Pig, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744549
Quantity
100 μL
Datasheet
Datasheet
Recommended RFX1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7563311
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7555164
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Cell-free protein synthesis (CFPS)
Validations
Cat. No.
ABIN3134194
Quantity
250 μg
Datasheet
Datasheet
Latest Publications for our RFX1 Products
: "RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction." in: Scientific reports, Vol. 8, Issue 1, pp. 210, (2018) (PubMed).: "Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation." in: Scientific reports, Vol. 6, pp. 19069, (2016) (PubMed).
: "RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells." in: Oncotarget, Vol. 5, Issue 13, pp. 4909-19, (2014) (PubMed).
: "RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells." in: Carcinogenesis, Vol. 35, Issue 12, pp. 2807-14, (2014) (PubMed).
: "SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 7, pp. 595-605, (2014) (PubMed).
Synonyms and alternative names related to RFX1
regulatory factor X1 (RFX1), regulatory factor X, 1 (influences HLA class II expression) (Rfx1), regulatory factor X1 (Rfx1), regulatory factor X, 1a (influences HLA class II expression) (rfx1a), AI047719, AI385641, EFC, RFX, zgc:162914Protein level used designations for RFX1
- MHC class II regulatory factor RFX
- MHC class II regulatory factor RFX1
- enhancer factor C
- regulatory factor X 1
- trans-acting regulatory factor 1
- transcription factor RFX1
- vregulatory factor X, 1 (influences HLA class II expression)
- regulatory factor X1
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