Retinoblastoma Protein (Rb) 抗体

Controls the progression of the cell cycle from G1 to S phase. Acts through the modulation of E2F action in response to D- type cyclins. Negative regulator of cell proliferation during leaf and gametophyte development. At later stages of development, restricts the progression through additional endocycles. Regulates the root stem cell pool size. Interaction with mastrevirus RepA or nanovirus Clink protein disrupts the RBR/E2F interaction and releases the transcription of replicative enzymes needed by the virus by increasing the E2F DNA-binding activity.