The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008].
Latest Publications for our RecQ Protein-Like (DNA Helicase Q1-Like) 抗体
Chappidi, Nascakova, Boleslavska, Zellweger, Isik, Andrs, Menon, Dobrovolna, Balbo Pogliano, Matos, Porro, Lopes, Janscak: "Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops." in: Molecular cell, (2019) (PubMed).
Wang, Grunseich, Fox, Burdick, Zhu, Ravazian, Hafner, Cheung: "Human proteins that interact with RNA/DNA hybrids." in: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).
Zellweger, Dalcher, Mutreja, Berti, Schmid, Herrador, Vindigni, Lopes: "Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells." in: The Journal of cell biology, Vol. 208, Issue 5, pp. 563-79, (2015) (PubMed).
Sharma, Phatak, Stortchevoi, Jasin, Larocque: "RECQ1 plays a distinct role in cellular response to oxidative DNA damage." in: DNA repair, Vol. 11, Issue 6, pp. 537-49, (2012) (PubMed).
Aliases for RecQ Protein-Like (DNA Helicase Q1-Like) 抗体
RecQ like helicase (RECQL) 抗体 RecQ helicase-like (recql) 抗体 ATP-dependent DNA helicase Q1 (CpipJ_CPIJ017275) 抗体 ATP-dependent DNA helicase Q1 (PAAG_01087) 抗体 RecQ like helicase (recql) 抗体 RecQ like helicase L homeolog (recql.L) 抗体 adenosylhomocysteinase pseudogene (LOC100151819) 抗体 RecQ protein-like (Recql) 抗体 RecQ like helicase (Recql) 抗体 DKFZp469B0921 抗体 MGC131022 抗体 RecQ1 抗体 recq1 抗体 RECQL 抗体 RECQL1 抗体 recql1 抗体 zgc:110631 抗体