RASSF1 抗体
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011].
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59 results
RASSF1
适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, 豚鼠, 兔
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our RASSF1 抗体
: "An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma." in: Oncotarget, Vol. 8, Issue 12, pp. 19712-19722, (2017) (PubMed).: "CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis." in: Molecular medicine reports, Vol. 11, Issue 4, pp. 3039-46, (2015) (PubMed).
: "Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma." in: International journal of oncology, Vol. 48, Issue 1, pp. 55-66, (2015) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Hypermethylation of RASSF1A in human and rhesus placentas." in: The American journal of pathology, Vol. 170, Issue 3, pp. 941-50, (2007) (PubMed).
: "Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6626-36, (2006) (PubMed).
: "The tumor suppressor RASSF1A in human carcinogenesis: an update." in: Histology and histopathology, Vol. 20, Issue 2, pp. 645-63, (2005) (PubMed).
: "Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter." in: Molecular and cellular biology, Vol. 25, Issue 10, pp. 3923-33, (2005) (PubMed).
Aliases for RASSF1 抗体
NPR2-like, GATOR1 complex subunit (NPRL2) 抗体Ras association (RalGDS/AF-6) domain family 1 (rassf1) 抗体
Ras association domain family member 1 (RASSF1) 抗体
putative rassf1 (Smp_157340) 抗体
Ras association domain family member 1 L homeolog (rassf1.L) 抗体
Ras association (RalGDS/AF-6) domain family member 1 (Rassf1) 抗体
Ras association domain family member 1 (Rassf1) 抗体
123F2 抗体
AA536941 抗体
AU044980 抗体
NORE2A 抗体
RASSF1 抗体
RASSF1A 抗体
Rassf1A 抗体
Rassf1B 抗体
Rassf1C 抗体
RDA32 抗体
REH3P21 抗体
wu:fc17f02 抗体
zgc:92505 抗体
zgc:112224 抗体
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