RASIP1 抗体
(Ras Interacting Protein 1 (RASIP1))
Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.
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Latest Publications for our RASIP1 抗体
: "Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11427-32, (2013) (PubMed).: "Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22353-61, (2004) (PubMed).
Aliases for RASIP1 抗体
Ras interacting protein 1 (RASIP1) 抗体Ras interacting protein 1 (Rasip1) 抗体
1110025D03Rik 抗体
2610025P08Rik 抗体
AI853551 抗体
RAIN 抗体
Rain 抗体
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