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RASIP1 抗体 (AA 620-700)

The 兔 多克隆 anti-RASIP1 antibody (ABIN7230920) specifically detects RASIP1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230920
发货至: 中国
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Quick Overview for RASIP1 抗体 (AA 620-700) (ABIN7230920)

抗原

See all RASIP1 抗体
RASIP1 (Ras Interacting Protein 1 (RASIP1))

适用

  • 9
  • 1
  • 1
人, 小鼠

宿主

  • 6
  • 2
  • 1

克隆类型

  • 9
多克隆

标记

  • 9
This RASIP1 antibody is un-conjugated

应用范围

  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    • 1
    AA 620-700

    原理

    Rabbit Anti-RAIN Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of RAIN protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RASIP1 (Ras Interacting Protein 1 (RASIP1))

    别名

    RAIN

    背景

    Ras-interacting protein 1, RainRequired for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

    分子量

    105kD

    基因ID

    54922

    UniProt

    Q5U651
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