RASGRP1 产品
(RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008].
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Featured RASGRP1 Categories
RASGRP1 抗体
High quality antibodies with extensive validation data.
RASGRP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RASGRP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6146720
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN652037
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7167163
Quantity
100 μg
Datasheet
Datasheet
Recommended RASGRP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3092824
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3137612
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2730515
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to RASGRP1
RAS guanyl releasing protein 1 (Rasgrp1), RAS guanyl releasing protein 1 (RASGRP1), CALDAG-GEFI, CALDAG-GEFII, hRasGRP1, Rasgrp, RASGRP, VProtein level used designations for RASGRP1
- RAS guanyl-releasing protein 1
- calDAG-GEFII
- calcium and DAG-regulated guanine nucleotide exchange factor II
- RAS guanyl nucleotide-releasing protein 1
- guanine nucleotide exchange factor, calcium- and DAG-regulated, Rap1A
- ras activator RasGRP
- CalDAG-GEF1
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