Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq, Jul 2008].
RAN binding protein 1 S homeolog (ranbp1.S) 蛋白 RAN binding protein 1 L homeolog (ranbp1.L) 蛋白 ran binding protein 1 (PVX_090070) 蛋白 RAN binding protein 1 (GL50803_16969) 蛋白 ran-specific GTPase-activating protein pseudogene (LOC100343953) 蛋白 RAN binding protein 1 (ranbp1) 蛋白 RAN binding protein 1 (RANBP1) 蛋白 RAN binding protein 1 (Ranbp1) 蛋白 hm:zeh1094 蛋白 HTF9A 蛋白 Htf9a 蛋白 MGC64314 蛋白 wu:fa96a09 蛋白 wu:fj39g07 蛋白 zeh1094 蛋白 zgc:85649 蛋白