RAD51C 抗体
(DNA Repair Protein RAD51 Homolog 3 (RAD51C))
This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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40 results :
RAD51C
适用: 人, 小鼠, 大鼠
WB, ELISA, IF, IHC, ICC
宿主: 兔
Polyclonal
unconjugated
RAD51C
适用: 人
WB, ELISA, IF, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
RAD51C
适用: 人, 猴
WB, ELISA, IF, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
RAD51C
适用: 人, 猴
WB, ELISA, IF, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our RAD51C 抗体
: "BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability." in: Nature communications, Vol. 8, Issue 1, pp. 1470, (2017) (PubMed).: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
: "Characterisation of the novel deleterious RAD51C p.Arg312Trp variant and prioritisation criteria for functional analysis of RAD51C missense changes." in: British journal of cancer, Vol. 117, Issue 7, pp. 1048-1062, (2017) (PubMed).
: "Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair." in: Oncogene, Vol. 33, Issue 40, pp. 4803-12, (2014) (PubMed).
: "RAD51C-deficient cancer cells are highly sensitive to the PARP inhibitor olaparib." in: Molecular cancer therapeutics, Vol. 12, Issue 6, pp. 865-77, (2013) (PubMed).
: "BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage." in: DNA repair, Vol. 12, Issue 4, pp. 306-11, (2013) (PubMed).
: "Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity." in: Molecular cancer research : MCR, Vol. 11, Issue 12, pp. 1564-73, (2013) (PubMed).
: "Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 29, pp. 11800-5, (2012) (PubMed).
: "MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition." in: Cancer research, Vol. 72, Issue 16, pp. 4037-46, (2012) (PubMed).
: "Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway." in: Molecular and cellular biology, Vol. 33, Issue 2, pp. 387-95, (2012) (PubMed).
Aliases for RAD51C 抗体
RAD51 paralog C (RAD51C) 抗体RAD51 paralog C (Rad51c) 抗体
Rad51 recombinase D (Rad51D) 抗体
RAD51 paralog C (rad51c) 抗体
Rad51 DNA recombinase 3 (RAD51C) 抗体
RAD51C protein (RAD51C) 抗体
RAD51 homolog C (Rad51c) 抗体
RAS associated with diabetes protein 51C (RAD51C) 抗体
ATRAD51C 抗体
BROVCA3 抗体
CG2412 抗体
Dm CG2412 抗体
Dmel\\CG2412 抗体
F4L23.21 抗体
FANCO 抗体
R51H3 抗体
RAD51C 抗体
Rad51c 抗体
Rad51l2 抗体
RAD51L2 抗体
RAS associated with diabetes protein 51C 抗体
RGD1563765 抗体
zgc:101596 抗体
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