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RAD17 蛋白

(RAD17)
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2008].

5 results

custom-made RAD17 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7564065
 
custom-made RAD17 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7555145
 
RAD17 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
产品编号 ABIN1317265
 
custom-made RAD17 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3135721
 
custom-made RAD17 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3094929
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • 适用
    • Human
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-681
    • AA 1-688
    • AA 1-584
  • 标记
    • His tag
    • Strep Tag
    • GST tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • antibodies-online

Aliases for RAD17 蛋白

RAD17 checkpoint clamp loader component (RAD17) 蛋白
RAD17 checkpoint clamp loader component (rad17) 蛋白
Rad17p (RAD17) 蛋白
RADIATION SENSITIVE 17 (ATRAD17) 蛋白
RAD17 checkpoint clamp loader component (Rad17) 蛋白
9430035O09Rik 蛋白
CCYC 蛋白
HRAD17 蛋白
K2A18.21 蛋白
K2A18_21 蛋白
MmRad24 蛋白
R24L 蛋白
RAD17 蛋白
RAD17SP 蛋白
RAD24 蛋白
RADIATION SENSITIVE 17 蛋白
zgc:91969 蛋白
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