PTPN1 蛋白
(Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PTPN1 Protein (AA 1-321) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (AA 1-435) (GST tag) | 人 | 小麦胚 |
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| PTPN1 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| PTPN1 Protein (AA 1-435) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| PTPN1 Protein (AA 1-432) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| PTPN1 Protein (AA 1-321) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (AA 2-321) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (DYKDDDDK Tag) | 人 | Insect cells (Sf9) |
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| PTPN1 Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| PTPN1 Protein (full length) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (AA 1-321) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (full length) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (AA 1-321) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| PTPN1 Protein (AA 1-432) (His tag) | 大鼠 | 酵母菌 |
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| PTPN1 Protein (AA 1-434) (His tag) | 小鸡 | 酵母菌 |
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| PTPN1 Protein (AA 1-321) (His tag) | 人 | Bacteria |
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| PTPN1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- EAA (Enzyme Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- PAA (Phosphatase Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- Insect cells (Sf9)
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ScA (Screening Assay: 所列应用)
- Func (Functional Studies: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ScA (Screening Assay: 所列应用)
- EK (Enzyme Kinetics: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ScA (Screening Assay: 所列应用)
- Func (Functional Studies: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ScA (Screening Assay: 所列应用)
- EK (Enzyme Kinetics: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 小鸡
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Aliases for PTPN1 蛋白
protein tyrosine phosphatase, non-receptor type 1 (PTPN1) 蛋白protein tyrosine phosphatase, non-receptor type 1 (Ptpn1) 蛋白
protein tyrosine phosphatase, non-receptor type 1 (ptpn1) 蛋白
protein tyrosine phosphatase, non-receptor type 1 L homeolog (ptpn1.L) 蛋白
CPTP1 蛋白
Ptp 蛋白
PTP-1B 蛋白
PTP-HA2 蛋白
PTP1B 蛋白
ptp1b 蛋白
PTPN1 蛋白
wu:fk54h03 蛋白
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