PTF1A 抗体
(Pancreas Specific Transcription Factor, 1a (PTF1A))
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008].
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Latest Publications for our PTF1A 抗体
: "LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function." in: Genes & development, Vol. 25, Issue 16, pp. 1674-9, (2011) (PubMed).: "Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 2, pp. 341-51, (2009) (PubMed).
: "Origin of climbing fiber neurons and their developmental dependence on Ptf1a." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 41, pp. 10924-34, (2007) (PubMed).
: "Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5193-8, (2007) (PubMed).
: "Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates." in: Developmental biology, Vol. 268, Issue 1, pp. 174-84, (2004) (PubMed).
Aliases for PTF1A 抗体
pancreas specific transcription factor, 1a (PTF1A) 抗体pancreas specific transcription factor, 1a (ptf1a) 抗体
pancreas specific transcription factor, 1a (Ptf1a) 抗体
bHLHa29 抗体
PTF1 抗体
PTF1-p48 抗体
PTF1A 抗体
Ptf1a/p48 抗体
PTF1p48 抗体
si:zc142h2.2 抗体
XPtf1a 抗体
zgc:112216 抗体
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