PSMD12 抗体
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq, Jul 2008].
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PSMD12
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, Hamster
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our PSMD12 抗体
: "Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane." in: The Journal of biological chemistry, Vol. 291, Issue 29, pp. 15082-92, (2016) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
: "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets." in: Nature genetics, Vol. 38, Issue 3, pp. 285-93, (2006) (PubMed).
: "Mammalian Cdh1/Fzr mediates its own degradation." in: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).
: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).
: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
: "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets." in: Nature genetics, Vol. 38, Issue 3, pp. 285-93, (2006) (PubMed).
: "Mammalian Cdh1/Fzr mediates its own degradation." in: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).
: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).
: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
Aliases for PSMD12 抗体
proteasome 26S subunit, non-ATPase 12 (psmd12) 抗体proteasome 26S subunit, non-ATPase 12 (PSMD12) 抗体
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (Psmd12) 抗体
proteasome 26S subunit, non-ATPase 12 (Psmd12) 抗体
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