Staphylokinase (Active) 蛋白
This Recombinant protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for Staphylokinase (Active) 蛋白 (ABIN988238)
抗原
Staphylokinase
蛋白类型
Recombinant
生物活性
Active
宿主
Staphylococcus
资源
大肠杆菌（E. Coli）
纯度
> 95 % by SDS-PAGE and HPLC analyses.
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序列
- SSSFDKGKYK KGDDASYFEP TGPYLMVNVT GVDGKRNELL SPRYVEFPIK PGTTLTKEKI EYYVEWALDA TAYKEFRVVE LDPSAKIEVT YYDKNKKKEE TKSFPITEKG FVVPDLSEHI KNPGFNLITK VVIEK
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产品特性
- Fully biologically active when compared to standard. The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 50,000U/mg.
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内毒素水平
- Level Less than 1EU/µg of rSAK as determined by LAL method
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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储存条件
- 4 °C
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- Staphylokinase
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背景
- Staphylokinase (SAK), a 16kDa profibrinolytic protein from the Staphylococcus aureus, has been demonstrated to induce highly fibrin-specific thrombolysis in both human plasma and in limited clinical trials. Recent studies on the thrombolytic potential of recombinant SAK in achieving early perfusion in myocardial infarction and in the dissolution of platelet-rich clot have clearly established its immense utility in clinical medicine as a thrombolytic agent and suggested that it can be developed as a potent clot-dissolving agent. Synonym: Staphylokinase. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
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分子量
- Approximately 15.6 kDa, a single non-glycosylated polypeptide chain containing 136 amino acids.
抗原
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