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CCL5 蛋白

This CCL5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN988213
发货至: 中国

Quick Overview for CCL5 蛋白 (ABIN988213)

抗原

See all CCL5 蛋白
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 98 % by SDS-PAGE and HPLC analyses.
  • 序列

    SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEM

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 30 ng/ml, corresponding to a specific activity of >, 3.3 × 104 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rHuRANTES/ CCL5 as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    别名

    RANTES/ CCL5

    背景

    CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells. Synonym: RANTES/ CCL5, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.

    分子量

    7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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