CCL5 Protein (AA 24-91)
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- 抗原 See all CCL5 蛋白
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-91
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Cell Migration Assay (CMA)
- 序列
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
- 产品特性
- Recombinant Human CCL5 (Rantes)
- 纯度
- > 97 % by SDS PAGE
- 内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.13 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL5 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- 储存条件
- -20 °C,-80 °C
- 储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - 有效期
- 12 months
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- 抗原
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- 别名
- CCL5 (Rantes) (CCL5 产品)
- 别名
- Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
- 背景
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
- 分子量
- 7.851 kDa
- UniProt
- P13501
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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