VEGFB 蛋白
Quick Overview for VEGFB 蛋白 (ABIN935902)
抗原
See all VEGFB 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- PVSQPDAPGH QRKVVSWIDV YTRATCQPRE VVVPLTVELM GTVAKQLVPS CVTVQRCGGC CPDDGLECVP TGQHQVRMQI LMIRYPSSQL GEMSLEEHSQ CECRPKKKDS AVKPDSPRPL CPRCTQHHQR PDPRTCRCRC RRRSFLRCQG RGLELNPDTC RCRKLRR
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产品特性
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Purified recombinant Human VEGF B protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) in the presence of human VEGF165. The expected ED50 for this effect is 1.0-2.0 µg/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Vascular Endothelial Growth Factor B (VEGFB) (AA 1-207) protein (GST tag)
VEGFB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor B (VEGFB) (Active) proteinVEGFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Vascular Endothelial Growth Factor B (VEGFB) (AA 22-207) (Active) protein (His tag)VEGFB 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
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别名
- VEGF B
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背景
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VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a "cysteine knot" like structural motif, but differ in their carboxyl-terminal domains.
Alternative Names: VEGF-related factor protein, VRF protein, Vascular Endothelial Growth Factor-B protein -
途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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