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SERPINB2 蛋白

SERPINB2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure Active
产品编号 ABIN935740
发货至: 中国
  • 抗原 See all SERPINB2 蛋白
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 4
    • 4
    • 2
    资源
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVT PMTPENFTSC GFMQQIQKGS YPDAILQAQA ADKIHSSFRS LSSAINASTG N YLLESVNK LFGEKSASFR EEYIRLCQKY YSSEPQAVDF LECAEEARKK INSWVKTQTK GK IPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REK LNIGYI EDLKAQILEL PYAGDVSMFL LLPDEIADVS TGLELLESEI TYDKLNKWTS KDKM AEDEV EVYIPQFKLE EHYELRSILR SMGMEDAFNK GRANFSGMSE RNDLFLSEVF HQAMV DVNE EGTEAAAGTG GVMTGRTGHG GPQFVADHPF LFLIMHKITN CILFFGRFSS P
    产品特性
    Purified recombinant Human PAI2 protein
    Expression System: E.coli
    Bioactivity: Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 370C. Half maximal inhibition against 1.0 µg/mL of single chain tPA was obtained at a concentration of 1.0 µg/mL
    纯度
    > 95 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product SERPINB2 蛋白
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    Lyophilized from 50 MM CH3COONa, with 100 mM NaCl.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    别名
    PAI2 (SERPINB2 产品)
    物质类
    Amino Acid
    背景
    PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47 kDa nonglycosylated intracellular protein which can be induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions.
    Alternative Names: Plasminogen Activator Inhibitor-2 protein, Urokinase Inhibitor protein, PAI 2, PAI-2 protein, PAI2, PAI-2 protein, PAI 2 protein, PAI-2
    途径
    Autophagy
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