Oncostatin M Protein (OSM)
Quick Overview for Oncostatin M Protein (OSM) (ABIN935703)
抗原
See all Oncostatin M (OSM) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
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产品特性
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Purified recombinant Human Oncostatin M protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag,Biotin)OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-239) protein (His-IF2DI Tag)OSM 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Oncostatin M (OSM) (AA 26-221) (Active) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Oncostatin M (OSM) (AA 26-252) proteinOSM 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Oncostatin M (OSM)
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别名
- Oncostatin M
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背景
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Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells.
Alternative Names: OSM protein -
分子量
- 26 kDa
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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