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Oncostatin M Protein (OSM)

OSM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935703
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 蛋白
    Oncostatin M (OSM)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 25
    • 5
    • 4
    • 3
    • 1
    • 1
    资源
    • 20
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
    产品特性
    Purified recombinant Human Oncostatin M protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product OSM 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    Oncostatin M (OSM)
    别名
    Oncostatin M (OSM 产品)
    背景
    Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells.
    Alternative Names: OSM protein
    分子量
    26 kDa
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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