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CCL4 蛋白

This Recombinant CCL4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935632
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL4 蛋白 (ABIN935632)

抗原

See all CCL4 蛋白
CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 10
  • 7
  • 4
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  • 2
  • 2
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  • 1

资源

  • 24
  • 5
  • 1
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  • 1
大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN

    产品特性

    Purified recombinant Human MIP1 beta protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 5.0-20.0 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    Supplied lyophilized with no additives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

    别名

    MIP1 beta

    背景

    Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
    Alternative Names: MIP beta-1 protein, MIP beta 1, MIP beta-1, ACT-2 protein, CCL4 protein, Macrophage Inflammatory Protein-1 beta protein, MIP-1 beta protein, MIP1 beta, MIP beta 1 protein

    分子量

    7.8 kDa
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