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CCL4 Protein (AA 24-92) (Biotin)

CCL4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS PAGE CMA Active
产品编号 ABIN6952193
发货至: 中国
  • 抗原 See all CCL4 蛋白
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-92
    宿主
    • 11
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    资源
    • 19
    • 5
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CCL4 protein is labelled with Biotin.
    应用范围
    Cell Migration Assay (CMA)
    序列
    APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
    产品特性
    Biotininylated Recombinant Human CCL4 (MIP-1beta)
    纯度
    > 97 % by SDS PAGE
    内毒素水平
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.32-1.3 nM determined by Migration Assay in cells expressing recombinant CCR5
    Top Product
    Discover our top product CCL4 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    储存条件
    -20 °C,-80 °C
    储存方法
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    有效期
    12 months
  • 抗原
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    别名
    CCL4 (MIP-1beta) (CCL4 产品)
    别名
    ACT2 Protein, AT744.1 Protein, G-26 Protein, HC21 Protein, LAG-1 Protein, LAG1 Protein, MIP-1-beta Protein, MIP1B Protein, MIP1B1 Protein, SCYA2 Protein, SCYA4 Protein, CCL4 Protein, K203 Protein, Mip1-b Protein, Scya4 Protein, MIP-1beta Protein, MIP-1BETA Protein, MIP1b Protein, SCY4A Protein, Act-2 Protein, MIP-1B Protein, Mip1b Protein, ACT-2 Protein, AT744.2 Protein, CCL4L Protein, SCYA4L Protein, SCYA4L1 Protein, SCYA4L2 Protein, C-C motif chemokine ligand 4 Protein, chemokine (C-C motif) ligand 4 Protein, chemokine (C-C motif) ligand 4-like 1 Protein, C-C motif chemokine ligand 4 like 1 Protein, CCL4 Protein, Ccl4 Protein, CCL4L1 Protein
    背景
    Monokine with inflammatory and chemokinetic properties binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
    分子量
    10.238 kDa
    UniProt
    P13236
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