IL-4 蛋白
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- 抗原 See all IL-4 (IL4) 蛋白
- IL-4 (IL4) (Interleukin 4 (IL4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- 大肠杆菌(E. Coli)
- 序列
- MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
- 产品特性
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Purified recombinant Rat IL4 protein
Expression System: E.coli
Bioactivity: Tested by its ability to suppress LPS-induced TNF-alpha and MIP-2 production in mouse splenocytes. - 纯度
- > 98 % pure
- 内毒素水平
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL4 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
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- 抗原
- IL-4 (IL4) (Interleukin 4 (IL4))
- 别名
- IL4 (IL4 产品)
- 背景
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IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.
Alternative Names: B cell stimulating factor protein, IL 4, BCDF protein, IL-4, Interleukin 4 protein, BSF-1 protein, IL 4 protein, IL-4 protein, IL4, BCGF protein, IL-4 protein - 分子量
- 14.0 kDa
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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