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IL-21 蛋白

This Recombinant IL-21 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935584
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-21 蛋白 (ABIN935584)

抗原

See all IL-21 (IL21) 蛋白
IL-21 (IL21) (Interleukin 21 (IL21))

蛋白类型

Recombinant

生物活性

Active

宿主

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小鼠

资源

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS

    产品特性

    Purified recombinant Mouse IL21 protein
    Expression System: E.coli
    Bioactivity: Determined by a cell proliferation assay using modified Ba/F3 cells. The expected ED50for this effect is 10-50 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Supplied as a lyophilized powder.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL21

    背景

    IL21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL4 of IgG production, and induction of apoptotic effects in naive B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL21 exerts its effect through binding to a specific type I cytokine receptor, IL21R, which also contains the gamma chain (?c) found in other cytokine receptors including IL2, IL4, IL7, IL9 and IL15.
    Alternative Names: IL-21 protein, IL21, IL-21, IL-21 protein, IL 21 protein, Interleukin 21 protein, IL 21

    分子量

    15 kDa

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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