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ICAM1 蛋白

This Recombinant ICAM1 protein is expressed in CHO Cells.
产品编号 ABIN935570
发货至: 中国

Quick Overview for ICAM1 蛋白 (ABIN935570)

抗原

See all ICAM1 蛋白
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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CHO Cells

纯度

> 98 % pure
  • 序列

    QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPGNNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE LAPLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVGEPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QLQTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALGDQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQETLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVPA QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELRVLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE

    产品特性

    Purified recombinant Human ICAM1 protein
    Expression System: CHO cells
    Bioactivity: ICAM-1 supported the adhesion of more than 50 % PMA-stimulated HSB2 cells to plates coated at 25ng/mL ICAM-1 concentration

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Supplied as a lyophilized powder.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    ICAM1

    物质类

    Viral Protein

    背景

    ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1.
    Alternative Names: major group rhinovirus receptor protein, ICAM1, CD54 antigen protein, ICAM 1, ICAM-1 protein, Intercellular adhesion molecule 1 protein, ICAM-1, ICAM-1 protein, ICAM 1 protein

    分子量

    72-80 kDa

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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