Purified recombinant Human ICAM1 protein Expression System: CHO cells Bioactivity: ICAM-1 supported the adhesion of more than 50 % PMA-stimulated HSB2 cells to plates coated at 25ng/mL ICAM-1 concentration
ICAM1
宿主: 大鼠
宿主: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
缓冲液
Supplied as a lyophilized powder.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
RT/-20 °C
抗原
ICAM1
(Intercellular Adhesion Molecule 1 (ICAM1))
别名
ICAM1
物质类
Viral Protein
背景
ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Alternative Names: major group rhinovirus receptor protein, ICAM1, CD54 antigen protein, ICAM 1, ICAM-1 protein, Intercellular adhesion molecule 1 protein, ICAM-1, ICAM-1 protein, ICAM 1 protein