IGFBP6 蛋白
Quick Overview for IGFBP6 蛋白 (ABIN935551)
抗原
See all IGFBP6 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
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产品特性
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Purified recombinant Human IGF BP6 protein
Expression System: Hi-5 cells
Bioactivity: Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 - 0.4 µg/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)
IGFBP6 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 26-238) protein (His tag)IGFBP6 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 28-240) protein (His tag)IGFBP6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 1-240) protein (GST tag)IGFBP6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)IGFBP6 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (Active) protein (His tag)IGFBP6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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说明
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
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别名
- IGF BP6
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背景
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6 is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid, and specifically inhibits IGF-II actions. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
Alternative Names: IGF BP-6 protein, IBP-6 protein, IGF BP 6, IGF BP6, IGF BP 6 protein, IGF BP-6 protein, IGF BP-6 -
分子量
- 22.6 kDa
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途径
- WNT signaling, Myometrial Relaxation and Contraction
抗原
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