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FGF acidic (Active) 蛋白

This Recombinant protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935373
发货至: 中国

Quick Overview for FGF acidic (Active) 蛋白 (ABIN935373)

抗原

FGF acidic

蛋白类型

Recombinant

生物活性

Active

宿主

  • 2
  • 1
  • 1

资源

  • 4
大肠杆菌(E. Coli)

纯度

> 95 % pure
  • 序列

    MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

    产品特性

    Purified recombinant Human FGF acidic protein
    Expression System: E.coli
    Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ? 0.5 ng/mL corresponding to a specific activity of ? 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ? 0.2 ng/mL in the presence of 10 µg/mL heparin, corresponding to a specific activity of ? 5 x 10^6 units/mg.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Supplied as a lyophilized powder.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    FGF acidic

    背景

    FGF acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF acidic has the ability to signal through all the FGF receptors.
    Alternative Names: FGF-1 protein, ECGF-beta protein, HBGF-1 protein, Fibroblast Growth Factor-acidic protein

    分子量

    15.9 kDa
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