FGF23 蛋白
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- 抗原 See all FGF23 蛋白
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI
- 产品特性
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Purified recombinant Human FGF23 protein
Expression System: E.coli - 纯度
- > 95 % pure
- 内毒素水平
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product FGF23 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
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- 抗原
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 别名
- FGF23 (FGF23 产品)
- 别名
- FGF23 Protein, ADHR Protein, FGFN Protein, HPDR2 Protein, HYPF Protein, PHPTC Protein, fibroblast growth factor 23 Protein, fgf23 Protein, FGF23 Protein, Fgf23 Protein
- 背景
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The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF23, FGF21 and FGF19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
Alternative Names: FGF-23 protein, FGF-23, FGF23, FGF 23, Fibroblast Growth Factor-23 protein, FGF 23 protein, FGF-23 protein - 分子量
- 22.5 kDa
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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