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WISP2 蛋白

This Recombinant WISP2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935289
发货至: 中国

Quick Overview for WISP2 蛋白 (ABIN935289)

抗原

See all WISP2 蛋白
WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 3
  • 3
  • 2

资源

  • 5
  • 1
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % pure
  • 序列

    MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF

    产品特性

    Purified recombinant Human CTGFL protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/mL in the presence of 15 ng/mL of human IGF-II.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1- 1.0 mg/mL. Do not raise to neutral pH.

    缓冲液

    Supplied lyophilized with no additives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原

    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

    别名

    CTGFL

    背景

    CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors.
    Alternative Names: WISP2 protein, CCN5 protein, CT-58 protein, Connective Tissue Growth Factor-Like protein protein

    分子量

    24.3 kDa

    途径

    WNT signaling, Growth Factor Binding
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