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Betacellulin Protein (BTC)

This Recombinant Betacellulin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935244
发货至: 中国
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Quick Overview for Betacellulin Protein (BTC) (ABIN935244)

抗原

See all Betacellulin (BTC) 蛋白
Betacellulin (BTC)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 13
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资源

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY

    产品特性

    Purified recombinant Human Betacellulin protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7units/mg.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Supplied as a lyophilized powder.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原

    Betacellulin (BTC)

    别名

    Betacellulin

    背景

    Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
    Alternative Names: BTC protein, beta Cellulin protein

    分子量

    9 kDa

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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