14-3-3 sigma/SFN Protein (AA 1-248)
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Quick Overview for 14-3-3 sigma/SFN Protein (AA 1-248) (ABIN935074)
抗原
See all 14-3-3 sigma/SFN (SFN) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-248
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序列
- MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
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产品特性
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Purified recombinant Human 14.3.3 sigma protein
Expression System: E.coli
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Stratifin (SFN) (AA 1-248) protein (His tag)
custom-made SFN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Stratifin (SFN) (AA 1-248) protein (His tag)custom-made SFN 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Stratifin (SFN) (AA 1-248) protein (GST tag)SFN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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应用备注
- 14.3.3 Sigma protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 50 mM NaCl and 10 % glycerol.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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别名
- 14.3.3 sigma
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背景
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14-3-3 sigma, also known as Stratifin (SFN), belongs to the 14-3-3 family. The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 sigma was identified as an epithelial cell marker and appeared to function as a tumor suppressor whose expression can be down regulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis. Recombinant human 14-3-3 sigma was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: HME1 protein, SFN protein, 14.3.3 sigma, Epithelial cell marker protein 1 protein, stratifin protein, 14-3-3 sigma protein, 14/3/3 sigma protein, YWHAS protein, 14-3-3 sigma, 14/3/3 sigma, 14-3-3 sigma -
分子量
- 27.7 kDa (248 AA)
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途径
- p53 Pathway, Myometrial Relaxation and Contraction
抗原
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