SPARC 蛋白
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北京 101111
Quick Overview for SPARC 蛋白 (ABIN925110)
抗原
See all SPARC 蛋白蛋白类型
宿主
宿主
纯度
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产品特性
- Cellular Localization: Bone, platelets, plasma (0.9 µg/mLl), serum (2.6 µg/mL).
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Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (AA 18-303) protein (His tag)
SPARC 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) protein (His tag)SPARC 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (AA 18-297) protein (His-IF2DI Tag)SPARC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (AA 1-303) protein (GST tag)SPARC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) protein (Fc Tag)SPARC 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (AA 18-303), (full length) protein (GST tag)SPARC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as solution in 0.02 M Tris, 0.15 M NaCl, pH 7.4.
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储存条件
- -80 °C
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- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
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别名
- Osteonectin
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背景
- Osteonectin is an acidic, noncollagenous glycoprotein originally isolated from fetal and adult bovine bone matrix. In vitro bovine bone osteonectin binds type I collagen, calcium (Kd=3x10 -7 M) and hydroxyapatite (Kd=8x10 -8 M) and has been shown to be a potent inhibitor of hydroxyapatite-seeded crystal growth. In this context it has been suggested that osteonectin may play an important role in the regulation of bone metabolism by binding hydroxyapatite to collagen. Recently, proteins homologous to osteonectin have been identified in a number of cell types, most of which are associated with extracellular matrix production. The amino acid sequence (from cDNA sequences) of one of these proteins, human placental SPARC is identical to human bone osteonectin. Osteonectin has also been identified as an alpha granule component of human platelets and is secreted during activation. A small portion of the secreted osteonectin is expressed on the platelet cell surface in an activation dependent manner. Purified platelet osteonectin is a single chain molecule which exhibits a slightly larger apparent molecular weight than that of osteonectin derived from bone. The NH2- terminal sequences of platelet- and bone- derived osteonectin are identical, but the two proteins differ with regard to the extent of glycosylation.
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分子量
- 29,000 (by sedimentation equilibrium)
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途径
- Autophagy
抗原
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