c-MYC Protein (AA 1-439, full length)
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北京 101111
Quick Overview for c-MYC Protein (AA 1-439, full length) (ABIN8117620)
抗原
See all c-MYC (MYC) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-439, full length
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原理
- Recombinant Human MYC protein
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序列
- MPLNVSFTNR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVTPF SLRGDNDGGG GSFSTADQLE MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKLA SYQAARKDSG SPNPARGHSV CSTSSLYLQD LSAAASECID PSVVFPYPLN DSSSPKSCAS QDSSAFSPSS DSLLSSTESS PQGSPEPLVL HEETPPTTSS DSEEEQEDEE EIDVVSVEKR QAPGKRSESG SPSAGGHSKP PHSPLVLKRC HVSTHQHNYA APPSTRKDYP AAKRVKLDSV RVLRQISNNR KCTSPRSSDT EENVKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT AYILSVQAEE QKLISEEDLL RKRREQLKHK LEQLRNSCA
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Myc Proto-Oncogene protein (MYC) (AA 330-439) protein (GST tag)
MYC 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Myc Proto-Oncogene protein (MYC) (AA 1-439) protein (GST tag)MYC 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Myc Proto-Oncogene protein (MYC) protein (Myc-DYKDDDDK Tag)MYC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Myc Proto-Oncogene protein (MYC) (AA 1-454) protein (His tag)MYC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Myc Proto-Oncogene protein (MYC) (AA 1-439), (full length) protein (GST tag)MYC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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说明
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Tag-Free
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限制
- 仅限研究用
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状态
- Liquid, Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50 % of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50 %. Customers could use it as reference.
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缓冲液
- If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5 % -50 % glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6 % Trehalose, pH 8.0.
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注意事项
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week.
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储存条件
- -20 °C,-80 °C
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储存方法
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
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有效期
- 6-12 months
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- MYC
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背景
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Relevance: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform
Alternative Name(s): Class E basic helix-loop-helix protein 39,Proto-oncogene c-Myc,Transcription factor p64
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分子量
- 48.9 kDa
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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