Neuregulin 1 Protein (NRG1) (AA 176-246)
Our Local Distributor
北京 101111
Quick Overview for Neuregulin 1 Protein (NRG1) (AA 176-246) (ABIN8057047)
抗原
See all Neuregulin 1 (NRG1) 蛋白蛋白类型
宿主
资源
纯度
-
-
产品特性
- AA 176-246
-
原理
- Recombinant Human Pro-Neuregulin-1/NRG1-β1 Protein (aa 176-246)
-
序列
- Thr176-Lys246
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
Neuregulin 1 (NRG1) (AA 20-242) protein (Fc Tag)
NRG1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Neuregulin 1 (NRG1) (AA 177-241) (Active) proteinNRG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Neuregulin 1 (NRG1) (AA 119-237) protein (His-IF2DI Tag)NRG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Neuregulin 1 (NRG1) (AA 177-241) protein (His-IF2DI Tag)NRG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Neuregulin 1 (NRG1) (AA 1-241) protein (GST tag)NRG1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
-
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
有效期
- 12 months
-
-
- Neuregulin 1 (NRG1)
-
别名
- Pro-Neuregulin-1
-
背景
- EGF,GGF,HGL,HRG1-beta 1,HRGA,NDF,NRG1,NRG1-beta 1,Neuregulin-1 beta 1,Pro-neuregulin-1,SMDF,neuregulin-1 (heregulin-1,NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.
-
分子量
-
Calculated MW: 8.2 kDa
Observed MW: 7 kDa
-
基因ID
- 3084
-
UniProt
- Q02297
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
-
