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FGF21 Protein (AA 30-210)

This Recombinant FGF21 protein is expressed in Mammalian Cells.
产品编号 ABIN8056955
发货至: 中国
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Quick Overview for FGF21 Protein (AA 30-210) (ABIN8056955)

抗原

See all FGF21 蛋白
FGF21 (Fibroblast Growth Factor 21 (FGF21))

蛋白类型

Recombinant

宿主

  • 40
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小鼠

资源

  • 34
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Mammalian Cells

应用范围

Immunogen (Imm)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 30-210

    原理

    Recombinant Mouse FGF21 Protein(Halo Tag)

    序列

    Tyr30-Ser210

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU/mg of the protein as determined by the LAL method

    Biological Activity Comment

    Not validated for activity
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    FGF21 (Fibroblast Growth Factor 21 (FGF21))

    别名

    FGF21

    背景

    Fibroblast growth factor 21,Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

    分子量

    Calculated MW: 53.8 kDa

    Observed MW: 53 kDa

    基因ID

    56636

    UniProt

    Q9JJN1

    途径

    RTK signaling
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