XRCC1 蛋白
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北京 101111
Quick Overview for XRCC1 蛋白 (ABIN7939755)
抗原
See all XRCC1 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant XRCC1 protein
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 152,621.24 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Recombinant XRCC1 protein is supplied at in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))
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别名
- XRCC1
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背景
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Protein Background: XRCC1 (DNA repair protein XRCC1) also known as RCC and SCAR26. XRCC1 is a scaffold protein that is recruited to SSBs by PARP1 and/or PARP2 activity through direct interaction betweenpoly (ADP-ribose) and the central BRCT domain in XRCC1. XRCC1 in turn interacts with and recruits the enzymes required for SSB repair, including DNA polymerase b, DNA ligase III, polynucleotide kinase/phosphatase and aprataxin. Hereditarymutations in XRCC1 and some of these protein partners result inneurodevelopmental disorders and/or progressive neurodegeneration.
Short Description: Recombinant XRCC1 protein that includes full length of human XRCC1 protein (accession number NP_006288.2) was expressed in Sf9 cells and contains an C-terminal His-FLAG tag with a molecular weight of 72.01 kDa. The purity of the protein is ≥ 80 % by SDS-PAGE.
Aliases: RCC, SCAR26
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途径
- DNA Damage Repair
抗原
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