UBE2M 蛋白
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Quick Overview for UBE2M 蛋白 (ABIN7939711)
抗原
See all UBE2M (ube2m) 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant UBE2M protein
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Ubiquitin-Conjugating Enzyme E2M (ube2m) (AA 1-183) protein (GST tag)
ube2m 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant UBE2M protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))
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别名
- UBE2M
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背景
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Protein Background: UBE2M (NEDD8-conjugating enzyme Ubc12) also known as hUbc12, UBC-RS2 and UBC12 UBE2M can accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.
Short Description: Recombinant UBE2M protein that includes full length of human UBE2M protein (accession number NP_003960.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 23.06 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: NEDD8-conjugating enzyme Ubc12, hUbc12, UBC-RS2, NEDD8-Carrier Protein, EC 2.3.2.34
抗原
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