UBE2I 蛋白
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北京 101111
Quick Overview for UBE2I 蛋白 (ABIN7939702)
抗原
See all UBE2I 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant UBE2I protein
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Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 1-158) protein (GST tag)
UBE2I 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 1-157), (partial) protein (GST tag)UBE2I 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)UBE2I 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)UBE2I 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant UBE2I protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
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别名
- UBE2I
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背景
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Protein Background: UBE2I (SUMO-conjugating enzyme UBC9) also known as C358B7.1, P18, UBC9. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. UBE2I can accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.
Short Description: Recombinant UBE2I protein that includes full length of human UBE2I protein (accession number NP_003336.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 20.17 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: Ubiquitin conjugating enzyme E2 I, SUMO conjugating enzyme UBC9, C358B7.1, P18, UBC9, ubiquitin carrier protein 9, SUMO protein ligase, P18
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
抗原
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