UBE2I 蛋白
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- 抗原 See all UBE2I 蛋白
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human UBE2I/UBC9 Protein
- 序列
- Met 1-Ser 158
- 产品特性
- A DNA sequence encoding the human UBE2I (P63279) (Met 1-Ser 158) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UBE2I 蛋白
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Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 1-158) protein (GST tag)
UBE2I 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 2-158) protein (His tag)Crystallography grade UBE2I 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 2-158) protein (His tag)Crystallography grade UBE2I 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (AA 1-157), (partial) protein (GST tag)UBE2I 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)UBE2I 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2I 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2I (UBE2I) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)UBE2I 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, 10 % glycerol, 2 mM DTT, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- 别名
- UBE2I/UBC9 (UBE2I 产品)
- 别名
- C358B7.1 Protein, P18 Protein, UBC9 Protein, ubc9 Protein, ube2ia Protein, zUbc9 Protein, 5830467E05Rik Protein, F830028O17Rik Protein, Ubce2i Protein, Ubce9 Protein, UbcE2A Protein, ubce9 Protein, T13J8.70 Protein, T13J8_70 Protein, UBIQUITIN-PROTEIN LIGASE Protein, ubiquitin conjugating enzyme 9 Protein, ubiquitin conjugating enzyme E2 I Protein, ubiquitin-conjugating enzyme E2Ib Protein, ubiquitin-conjugating enzyme E2L Protein, ubiquitin-conjugating enzyme E2I Protein, ubiquitin conjugating enzyme E2I S homeolog Protein, ubiquitin conjugating enzyme 9 Protein, SUMO-conjugating enzyme UBC9 Protein, UBE2I Protein, ube2ib Protein, UBE2L Protein, Ube2i Protein, ube2i.S Protein, UBC9 Protein, ubc-9 Protein, LOC108703134 Protein
- 背景
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Background: UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation; ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction; and thereby the fate of the substrate; is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space; a highly sophisticated conjugation machinery has been developed. In a sequential manner; ubiquitin becomes activated by an ubiquitin-activating enzyme (E1); which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next; ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system; wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans.
Synonym: SUMO-Conjugating Enzyme UBC9; SUMO-Protein Ligase; Ubiquitin Carrier Protein 9; Ubiquitin Carrier Protein I; Ubiquitin-Conjugating Enzyme E2 I; Ubiquitin-Protein Ligase I; p18; UBE2I; UBC9; UBCE9
- UniProt
- P63279
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
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