ERBB3 Protein (AA 665-1342)
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Quick Overview for ERBB3 Protein (AA 665-1342) (ABIN7939510)
抗原
See all ERBB3 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 665-1342
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原理
- Recombinant ErbB3 / HER3 (665-1342) protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant ErbB3 / HER3 (665-1342) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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别名
- ErbB3 & HER3
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背景
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Protein Background: ErbB3 (Receptor tyrosine-protein kinase erbB-3) is a tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Short Description: Recombinant ErbB3 / HER3 (665-1342) protein that includes amino acids 665-1342 of human ErbB3 protein (accession number NP_001973.2) was expressed in a baculovirus expression system and contains an N-terminal FLAG tag. The molecular weight of the protein is 76.52 kDa.
Aliases: Receptor tyrosine protein kinase erbB-3, HER3, Oncogene Homolog 3, LCCS2, FERLK, LCCS2, FERLK, ErbB-3, ErbB3-S, EC 2.7.10
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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