PARP3 蛋白
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Quick Overview for PARP3 蛋白 (ABIN7939433)
抗原
See all PARP3 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant PARP-3 protein
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Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (AA 1-533) protein (GST tag)
PARP3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PARP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant PARP3 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
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别名
- PARP-3
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背景
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Protein Background: PARP3 (Protein mono-ADP-ribosyltransferase PARP3), also known as ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1 and PADPRT-3. PARP3 is a Mono-ADP-ribosyltransferase that mediates mono-ADP ribosylation of target proteins and plays a key role in the response to DNA damage. Mediates mono-ADP-ribosylation of glutamate, aspartate or lysine residues on target proteins. Involved in DNA repair by mediating mono-ADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, such as histone H2B, XRCC5 and XRCC6. Involved in single-strand break repair by catalyzing mono-ADP-ribosylation of histone H2B on 'Glu-2' (H2BE2ADPr) of nucleosomes containing nicked DNA.
Short Description: Recombinant PARP3 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_005476.4) with an N-terminal His and FLAG tag. The molecular weight of the protein is 64.6 kDa.
Aliases: Protein mono ADP ribosyltransferase PARP3, ADPRT3, ARTD3, IRT1
抗原
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