PARP3 Protein (His-GST)
This Recombinant PARP3 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7317627
发货至:
中国
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Quick Overview for PARP3 Protein (His-GST) (ABIN7317627)
抗原
See all PARP3 蛋白
PARP3
(Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
蛋白类型
Recombinant
宿主
人
资源
Baculovirus infected Insect Cells
纯度
> 85 % as determined by reducing SDS-PAGE.
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标记
- This PARP3 protein is labelled with His-GST.
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原理
- Recombinant Human PARP-3/PARP3 Protein (His & GST Tag)
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序列
- Met 1-Leu 533
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产品特性
- A DNA sequence encoding the C-terminal segment of human PARP3 isoform 1 (Q9Y6F1-1) (Met 1-Leu 533) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (AA 1-533) protein (GST tag)
PARP3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PARP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
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别名
- PARP-3/PARP3
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背景
- ADPRT3,ADPRTL2,ADPRTL3,ARTD3,IRT1,PADPRT-3,Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
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分子量
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Calculated MW: 87.8 kDa
Observed MW: 95 kDa
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基因ID
- 10039
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UniProt
- Q9Y6F1
抗原
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