MBD4 Protein (Methyl-CpG-binding domain)
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Quick Overview for MBD4 Protein (Methyl-CpG-binding domain) (ABIN7939275)
抗原
See all MBD4 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- Methyl-CpG-binding domain
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原理
- Recombinant MBD4-MBD protein
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Methyl-CpG Binding Domain Protein 4 (MBD4) (AA 1-574) protein (GST tag)
MBD4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Methyl-CpG Binding Domain Protein 4 (MBD4) (AA 68-300) protein (His-IF2DI Tag)MBD4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant MBD4-MBD protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
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别名
- MBD4
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背景
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Protein Background: MBD4 (Methyl-CpG-binding domain protein 4) can mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methylCpG-binding protein.
Short Description: Recombinant MBD4-MBD protein that includes amino acids 71-159 of human MBD4 protein (accession number NP_003916.1) was expressed in E. coli cells with an N-terminal 6xHis tag. The molecular weight of the protein is 12.31 kDa.
Aliases: Methyl-CpG-binding domain protein 4, MED1
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途径
- DNA Damage Repair
抗原
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