GAMT 蛋白
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北京 101111
Quick Overview for GAMT 蛋白 (ABIN7938893)
抗原
See all GAMT 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant GAMT protein
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Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag)
GAMT 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GAMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236), (full length) protein (His tag)GAMT 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant GAMT protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
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别名
- GAMT
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背景
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Protein Background: Guanidinoacetate N-methyltransferase is also known as GAMT.The main function of GAMT is Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively inherited disorder of creatine biosynthesis . GAMT enzyme deficiency caused by mutations in the GAMT gene results in the depletion of creatine and accumulation of guanidinoacetate (GAA). Creatine has a buffering and transport function of high-energy phosphates in brain and muscle and is essential for growth cone migration, dendritic and axonal elongation, neurotransmitter release, and cotransmission on gamma amino butyric acid (GABA) postsynaptic receptors in the central nervous system.
Short Description: Recombinant GAMT protein was expressed in E.coli as the full length protein (accession number NP_000147.1) with an N-terminal 6xHis tag. The molecular weight of the protein is 28.11 kDa.
Aliases: Guanidinoacetate N-methyltransferase
抗原
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