GAMT Protein (His tag)
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- 抗原 See all GAMT 蛋白
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GAMT protein is labelled with His tag.
- 原理
- Recombinant Human GAMT Protein (His Tag)
- 序列
- Met 1-Gly236
- 产品特性
- Recombinant Human Guanidinoacetate N-methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product GAMT 蛋白
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Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag)
GAMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Guanidinoacetate N-Methyltransferase (GAMT) (AA 138-235) protein (GST tag)GAMT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236), (full length) protein (His tag)GAMT 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)GAMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GAMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mMDTT, pH 8.0 .
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- 别名
- GAMT (GAMT 产品)
- 别名
- gamt Protein, zgc:123136 Protein, CCDS2 Protein, PIG2 Protein, TP53I2 Protein, AA571402 Protein, Spintz1 Protein, MGC75698 Protein, GAMT Protein, GMT Protein, guanidinoacetate N-methyltransferase L homeolog Protein, guanidinoacetate N-methyltransferase S homeolog Protein, guanidinoacetate N-methyltransferase Protein, guanidinoacetate methyltransferase Protein, gamt.L Protein, gamt.S Protein, gamt Protein, GAMT Protein, Gamt Protein
- 背景
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Background: GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.
Synonym: Guanidinoacetate N-methyltransferase, GAMT, PIG2,TP53I2
- 分子量
- 29.5 kDa
- UniProt
- Q14353
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