EPH Receptor A5 Protein (EPHA5) (AA 620-1037)
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Quick Overview for EPH Receptor A5 Protein (EPHA5) (AA 620-1037) (ABIN7938800)
抗原
See all EPH Receptor A5 (EPHA5) 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 620-1037
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原理
- Recombinant EPHA5 (620-1037) protein
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EPH Receptor A5 (EPHA5) (AA 25-572) (Active) protein (His tag)
EPHA5 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A5 (EPHA5) (AA 26-573) (Active) protein (His tag)EPHA5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A5 (EPHA5) (AA 27-412) (Active) protein (His tag)EPHA5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A5 (EPHA5) (AA 25-573) protein (His tag)EPHA5 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, AM, ADA, IA
EPH Receptor A5 (EPHA5) protein (DYKDDDDK Tag)EPHA5 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
EPH Receptor A5 (EPHA5) protein (DYKDDDDK-His Tag)EPHA5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Recombinant EPHA5 (620-1037) protein is supplied 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- EPH Receptor A5 (EPHA5)
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别名
- EPHA5
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背景
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Protein Background: EPHA5 (Ephrin type-A receptor 5) is a receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 also plays a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.
Short Description: Recombinant EPHA5 (620-1037) protein that includes amino acids 620-1037of human EPHA5 protein (accession number NP_004430.4) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 48.41 kDa.
Aliases: Ephrin type-A receptor 5, EPHA5, CEK7, EHK1, Hek7, TYRO4
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途径
- RTK signaling
抗原
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