DDX3X 蛋白
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北京 101111
Quick Overview for DDX3X 蛋白 (ABIN7938752)
抗原
See all DDX3X 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant DDX3X protein
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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (AA 1-662) protein (GST tag)
DDX3X 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) protein (Myc-DYKDDDDK Tag)DDX3X 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant DDX3X protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
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别名
- DDX3X
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背景
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Protein Background: DDX3X (ATP-dependent RNA helicase DDX3X) is a multifunctional ATP-dependent RNA helicase belonging to the DEAD-box protein family, which is critically involved in numerous aspects of RNA metabolism. Its primary function is to unwind RNA secondary structures, an essential activity that facilitates key processes including transcription, mRNA splicing, nuclear export, translation initiation, and the assembly of stress granules. Furthermore, DDX3X plays vital roles in innate immune signaling pathways by modulating the activity of key kinases and interferon responses. Due to its central role in gene expression and cell growth, mutations in the DDX3X gene are linked to neurodevelopmental disorders and various cancers, highlighting its importance in cellular homeostasis and disease.
Short Description: Recombinant DDX3X protein was expressed in a baculovirus expression system as the full length protein (accession number NP_001347.3) with an N-terminal FLAG tag. The molecular weight of DDX3X is 74.51 kDa.
Aliases: ATP-dependent RNA helicase DDX3X, DEAD-Box Helicase, DDX3X, DDX3, HLP2
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途径
- Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
抗原
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